Skip to main content

Table 3 Test characteristics of different trigger factors in the internal validation cohort

From: Identification and validation of objective triggers for initiation of resuscitation management of acutely ill non-trauma patients: the INITIATE IRON MAN study

Trigger factor

AUC (range)

Sensitivity, %

Specificity, %

PPV, %

NPV, %

qSOFA ≥ 2 points

0.56 (0.48–0.64)

11.8

100

100

93.9

NEWS ≥ 7 points

0.66 (0.58–0.74)*

32.4

99.9

95.7

95.3

Iteration 1

0.92 (0.87–0.97)*

85.3

98.7

82.9

98.9

Iteration 2

0.91 (0.86–0.97)*

83.8

98.9

85.1

98.8

Iteration 3

0.99 (0.97–1.00)*

98.5

98.6

83.3

99.9

  1. AUC, area under the receiver operating characteristics curve; NEWS, National Early Warning Score; NPV, negative predictive value; PPV, positive predictive value; qSOFA, Quick Sequential Organ Failure Assessment Score
  2. *p < 0.0001
Back to article page

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

ISSN: 1757-7241