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Table 2 Demographics and clinical data of isolated TBI patients by survivors and non-survivors

From: Relationship between admission coagulopathy and prognosis in children with traumatic brain injury: a retrospective study

  Isolated
TBI patients
(n = 137)
Survivors
(n = 118)
Non-survivors
(n = 19)
P value
Baseline Demographics
 Age, M 36.0 (12.5–79.0) 45.0 (13.0–80.0) 17.0(11.0–58.0) 0.112
 Weight, kg 15.0 (10.0–22.0) 15.5 (10.0–23.0) 12.0 (9.0–15.0) 0.117
 Gender, male, n (%) 78 (56.9 %) 69 (58.5 %) 9 (47.4 %) 0.456
Injury severity
 GCS 9 (7–12) 9 (7–12) 6 (4–8) 0.001
 PTS 6 (4–8) 7 (4–8) 4 (2–6) 0.001
 ISS 16 (9–18) 16 (9–16) 16 (9–25) 0.119
Mechanism of injury     0.668
 Traffic, n (%) 43 (31.4 %) 39 (33.1 %) 4 (21.1 %)  
 Fall, n (%) 63 (46.0 %) 54 (45.8 %) 9 (47.4 %)  
 Others, n (%) 31 (22.6 %) 25 (21.2 %) 6 (31.6 %)  
 Abnormal pupil, n (%) 44 (32.1 %) 28 (23.7 %) 16 (84.2 %) < 0.001
 Hypotension, n (%) 12 (8.8 %) 9 (7.6 %) 3 (15.8 %) 0.373
Laboratory investigations
 Lactate, mmol/L 1.4 (0.8–3.4) 1.2 (0.7–2.7) 4.4 (2.8–8.3) < 0.001
 INR 1.12 (1.03–1.24) 1.11 (1.03–1.20) 1.22 (1.09–1.49) 0.027
 APTT, s 28.6 (25.0-33.2) 27.7 (24.7–32.7) 29.7 (27.5–47.4) 0.034
 Fibrinogen, mg/dL 143.0
(97.0-190.0)
150.0
(110.0-194.0)
71.0
(105.0-157.0)
0.024
 TT, s 18.4 (17.3–21.2) 18.3 (17.1–20.7) 18.9 (17.9–22.1) 0.082
 D-dimer, ug/L 9810
(2385–17,865)
10,430
(2413–18,458)
5540
(1570–16,600)
0.645
 PLT, /uL 283.0
(214.5-344.5)
283.0
(216.5–343.0)
262.0
(203.0-420.0)
0.830
 Hgb, g/L 101.0
(81.5-112.5)
103.0
(81.8-114.3)
90.0
(78.0-102.0)
0.044
 WBC, *10^9/L 15.7
(11.9–21.1)
15.7
(11.9–21.0)
14.3
(11.4–21.7)
0.746
  1. Data are shown as the median (interquartile range) or a number (percentage)
  2. M month, GCS Glasgow Coma Score, PTS Pediatric Trauma Score, INR International normalized ratio, APTT activated partial thromboplastin time, TT Thrombin time, PLT platelet count, Hgb hemoglobin, WBC white blood cell