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Table 1 Summary of oxygen transport, physiologic, and coagulation measurements.

From: Systemic central venous oxygen saturation is associated with clot strength during traumatic hemorrhagic shock: A preclinical observational model

 

Baseline

Hemorrhagic Shock

     
 

Mean

Mean

Mean Diff

Std Err Diff

95% CI Diff.

p value

Hemodynamics/Perfusion

       

MAP (mmHg)

110.1

29.7

-80.4

2.9

-86.7

-74.2

< 0.001

VO2 (ml/kg/min)

4.8

3.9

-1.1

0.1

-1.2

-0.9

< 0.001

ScvO2 (%)

65.1

18.4

-47.7

2.2

-52.1

-43.3

< 0.001

BE

1.8

-3.5

-5.6

0.7

-7.1

-4.2

< 0.001

Lactate (mmol/L)

1.5

7.1

+5.8

0.4

4.9

6.6

< 0.001

pH

7.42

7.35

-0.07

0.01

-0.09

-0.05

< 0.001

Coagulation

       

PT (sec)

13.1

13.8

+0.7

0.3

0

1.4

0.048

aPTT (sec)

25.3

23

-2.3

1.7

-6.2

1.6

0.207

Fibrinogen (mg/dl)

154.5

82.8

-87.8

15.4

-121.5

-54.2

< 0.001

Thrombelastography

      

R (min)

5.4

5.1

0.0

0.4

-0.8

0.8

1.0

K (min)

1.5

1.5

0.0

0.1

-0.2

0.2

1.0

Angle (°)

70.5

70.2

-0.8

1.9

-3.3

4.9

0.67

MA (mm)

68.7

65.2

-3.5

0.9

-5.3

-1.7

< 0.001

G (dynes/cm sqr.)

11275.2

9592.3

-1660.6

399.8

-2508.2

813.1

< 0.001

Cell Counts

       

WBC (10^9/L)

13.9

14.5

-0.2

0.8

-1.9

1.5

0.83

Hgb (g/dl)

9.9

8.9

-1.0

0.2

-1.5

-0.5

< 0.001

Hct (%)

29.8

27

-2.7

0.6

-3.9

-1.5

< 0.001

Plt (10^9/L)

299.2

270.2

-24.7

10.6

-46.4

3

0.27

  1. Data presented as mean, mean difference and standard error of the difference with 95% confidence intervals. Baseline measurements made prior to onset of hemorrhagic shock. Hemorrhagic shock measurements made after hemorrhage and a period of shock when Oxygen Debt = 80 ml/kg. All metabolic, coagulation, and cell counts measured from central venous blood samples. VO2= Total body oxygen consumption; ScvO2%= percent systemic central venous oxyhemoglobin saturation; BE = base excess of the extracellular fluid; PT = Prothrombin Time, aPTT = Activated Partial Thromboplastin Time; R = clot onset time, K = clot kinetics time, Angle = clotting angle, MA = clot maximal amplitude, G = clot shear modulus, WBC = white blood cell count; Hgb = hemoglobin concentration; Hct = percent hematocrit; Plt = Platelet Count
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Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

ISSN: 1757-7241