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Table 4 Delayed bleeding risk according to the two different sensitivity analyses performed

From: Incidence of delayed bleeding in patients on antiplatelet therapy after mild traumatic brain injury: a systematic review and meta-analysis

Study

MTBI

Sensitivity

ANTONI_2019

NA

1.85% (0.23–6.53%)

BATTLE_2017

NA

2.27% (0.06–12.02%)

CHENOWETH_2018

NA

7.11% (3.94–11.64%)

ERNSTBRUNNER_2016

1.05% (0.29–2.66%)

1.05% (0.29–2.66%)

GALLIAZZO_2019

1.53% (0.19–5.41%)

1.53% (0.19–5.41%)

GANETSKY_2017

NA

3.61% (2.30–5.37%)

HILL_2018

NA

3.29% (1.33–6.65%)

HUANG_2019

NA

2.52% (0.52–7.19%)

MANN_2018

NA

0.00% (0.00–3.18%)

NISHIJIMA_2012

0.00% (0.00–1.53%)

1.23% (0.26–3.57%)

PECK_2011

NA

0.00% (0.00–3.52%)

SCANTLING_2017

1.21% (0.15–4.31%)

1.2% (0.15–4.28%)

STANITSAS_2016

NA

0.00% (0.00–8.81%)

SWAP_2016

NA

2.31% (0.85–4.95%)

TAUBER_2009

4.00% (1.10–9.93%)

4.00% (1.10–9.93%)

TAYLOR_2012

NA

0.00% (0.00–4.25%)

No. studies

5

16

DB mean estimated risk

1.04% (0.15–2.49%)

1.70% (0.93–2.67%)

p value for heterogeneity

p = 0.0334

p = 0.0012

I2 statistic

62%

60%

  1. The results are presented as the mean estimates of delayed bleeding risk and 95% confidence intervals (in parentheses). GCS = Glasgow Coma Scale; MTBI = mild traumatic brain injury: includes only studies enrolling patients with TBI and a GCS ≥ 13; Sensitivity = includes all the studies considering unexplained deaths and patients lost at follow-up as events (i.e. delayed bleeding); No. studies = number of the studies included in the analysis; NA = not assessed in the corresponding original study