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Table 3 Comparison between isolated TBI patients and polytrauma patients

From: Relationship between admission coagulopathy and prognosis in children with traumatic brain injury: a retrospective study

  Isolated TBI
(n = 137)
TBI + other
(n = 144)
P value
Baseline Demographics
  Age, M 36.0 (12.5–79.0) 60.5 (29.3–96.0) < 0.001
 Weight, kg 15.0 (10.0–22.0) 19.5 (13.6–25.0) 0.001
 Gender, male, n (%) 78 (56.9 %) 92 (63.9 %) 0.233
Injury severity
 GCS 9 (7–12) 7 (5–8) < 0.001
 PTS 6 (4–8) 4 (2–6) < 0.001
 ISS 16 (9-17.5) 25 (18–34) < 0.001
Mechanism of injury    < 0.001
 Traffic, n (%) 43 (31.4 %) 66 (45.8 %)  
 Fall, n (%) 63 (46.0 %) 72 (50.0 %)  
 Others, n (%) 31 (22.6 %) 6 (4.2 %)  
 Abnormal pupil 44 (32.1 %) 65 (45.1 %) 0.028
 Hypotension, n (%) 12 (8.8 %) 22 (15.3 %) 0.103
Laboratory investigations
 Lactate, mmol/L 1.4 (0.8–3.4) 2.8 (1.1–4.4) 0.001
 INR 1.12 (1.03–1.24) 1.24 (1.12–1.51) < 0.001
 APTT, s 28.6 (25.0-33.2) 30.4 (27.4–39.2) 0.001
 Fibrinogen, mg/dL 143.0 (97.0-190.0) 123.0 (72.0-178.0) 0.033
 TT, s 18.4 (17.3–21.2) 18.9 (17.3–21.8) 0.26
 D-dimer, ug/L 9810
(2385–17,865)
16,775 (7098–28,523) < 0.001
 PLT, /uL 283.0 (214.5-344.5) 247.5 (167.8-299.5) 0.001
 Hgb, g/L 101.0 (81.5-112.5) 98.0 (81.3–110.0) 0.283
 WBC, *10^9/L 15.7(11.9–21.1) 13.1(12.7–22.0) 0.120
  1. Data are shown as the median (interquartile range) or a number (percentage)
  2. M month, GCS Glasgow Coma Score, PTS Pediatric Trauma Score, ISS Injury Severity Score, INR International normalized ratio, APTT activated partial thromboplastin time, TT Thrombin time, PLT platelet count, Hgb hemoglobin, WBC white blood cell