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Table 3 Comparison between isolated TBI patients and polytrauma patients

From: Relationship between admission coagulopathy and prognosis in children with traumatic brain injury: a retrospective study

 

Isolated TBI

(n = 137)

TBI + other

(n = 144)

P value

Baseline Demographics

  Age, M

36.0 (12.5–79.0)

60.5 (29.3–96.0)

< 0.001

 Weight, kg

15.0 (10.0–22.0)

19.5 (13.6–25.0)

0.001

 Gender, male, n (%)

78 (56.9 %)

92 (63.9 %)

0.233

Injury severity

 GCS

9 (7–12)

7 (5–8)

< 0.001

 PTS

6 (4–8)

4 (2–6)

< 0.001

 ISS

16 (9-17.5)

25 (18–34)

< 0.001

Mechanism of injury

  

< 0.001

 Traffic, n (%)

43 (31.4 %)

66 (45.8 %)

 

 Fall, n (%)

63 (46.0 %)

72 (50.0 %)

 

 Others, n (%)

31 (22.6 %)

6 (4.2 %)

 

 Abnormal pupil

44 (32.1 %)

65 (45.1 %)

0.028

 Hypotension, n (%)

12 (8.8 %)

22 (15.3 %)

0.103

Laboratory investigations

 Lactate, mmol/L

1.4 (0.8–3.4)

2.8 (1.1–4.4)

0.001

 INR

1.12 (1.03–1.24)

1.24 (1.12–1.51)

< 0.001

 APTT, s

28.6 (25.0-33.2)

30.4 (27.4–39.2)

0.001

 Fibrinogen, mg/dL

143.0 (97.0-190.0)

123.0 (72.0-178.0)

0.033

 TT, s

18.4 (17.3–21.2)

18.9 (17.3–21.8)

0.26

 D-dimer, ug/L

9810

(2385–17,865)

16,775 (7098–28,523)

< 0.001

 PLT, /uL

283.0 (214.5-344.5)

247.5 (167.8-299.5)

0.001

 Hgb, g/L

101.0 (81.5-112.5)

98.0 (81.3–110.0)

0.283

 WBC, *10^9/L

15.7(11.9–21.1)

13.1(12.7–22.0)

0.120

  1. Data are shown as the median (interquartile range) or a number (percentage)
  2. M month, GCS Glasgow Coma Score, PTS Pediatric Trauma Score, ISS Injury Severity Score, INR International normalized ratio, APTT activated partial thromboplastin time, TT Thrombin time, PLT platelet count, Hgb hemoglobin, WBC white blood cell