Isolated TBI (n = 137) | TBI + other (n = 144) | P value | ||||
---|---|---|---|---|---|---|
Baseline Demographics | ||||||
Age, M | 36.0 (12.5–79.0) | 60.5 (29.3–96.0) | < 0.001 | |||
Weight, kg | 15.0 (10.0–22.0) | 19.5 (13.6–25.0) | 0.001 | |||
Gender, male, n (%) | 78 (56.9 %) | 92 (63.9 %) | 0.233 | |||
Injury severity | ||||||
GCS | 9 (7–12) | 7 (5–8) | < 0.001 | |||
PTS | 6 (4–8) | 4 (2–6) | < 0.001 | |||
ISS | 16 (9-17.5) | 25 (18–34) | < 0.001 | |||
Mechanism of injury | < 0.001 | |||||
Traffic, n (%) | 43 (31.4 %) | 66 (45.8 %) | ||||
Fall, n (%) | 63 (46.0 %) | 72 (50.0 %) | ||||
Others, n (%) | 31 (22.6 %) | 6 (4.2 %) | ||||
Abnormal pupil | 44 (32.1 %) | 65 (45.1 %) | 0.028 | |||
Hypotension, n (%) | 12 (8.8 %) | 22 (15.3 %) | 0.103 | |||
Laboratory investigations | ||||||
Lactate, mmol/L | 1.4 (0.8–3.4) | 2.8 (1.1–4.4) | 0.001 | |||
INR | 1.12 (1.03–1.24) | 1.24 (1.12–1.51) | < 0.001 | |||
APTT, s | 28.6 (25.0-33.2) | 30.4 (27.4–39.2) | 0.001 | |||
Fibrinogen, mg/dL | 143.0 (97.0-190.0) | 123.0 (72.0-178.0) | 0.033 | |||
TT, s | 18.4 (17.3–21.2) | 18.9 (17.3–21.8) | 0.26 | |||
D-dimer, ug/L | 9810 (2385–17,865) | 16,775 (7098–28,523) | < 0.001 | |||
PLT, /uL | 283.0 (214.5-344.5) | 247.5 (167.8-299.5) | 0.001 | |||
Hgb, g/L | 101.0 (81.5-112.5) | 98.0 (81.3–110.0) | 0.283 | |||
WBC, *10^9/L | 15.7(11.9–21.1) | 13.1(12.7–22.0) | 0.120 |