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Table 1 Demographics and clinical data of all TBI patients by survivors and non-survivors

From: Relationship between admission coagulopathy and prognosis in children with traumatic brain injury: a retrospective study

 

All patients

(n = 281)

Survivors

(n = 228)

Non-survivors

(n = 53)

P value

Baseline Demographics

 Age, M

50.0 (19.5–87.0)

51.0 (20.3–87.0)

49.0 (18.0-85.5)

0.678

 Weight, kg

17.0 (11.3–24.0)

17.5 (11.0–25.0)

15.0 (12.0-21.3)

0.419

 Gender, male, n (%)

170 (60.5 %)

141 (61.8 %)

29 (54.7 %)

0.339

Injury severity

 GCS

8 (6–10)

8 (7–11)

5 (3–7)

< 0.001

 PTS

5 (3–7)

5 (3–7)

2 (1–4)

< 0.001

 ISS

18 (13–27)

18 (9–25)

25 (18–30)

0.003

Mechanism of injury

   

0.505

 Traffic, n (%)

109 (38.8 %)

92 (40.4 %)

17 (32.1 %)

 

 Fall, n (%)

135 (48.0 %)

106 (46.5 %)

29 (54.7 %)

 

 Others, n (%)

37 (13.2 %)

30 (13.2 %)

7 (13.2 %)

 

Lesion type

 EDH, n (%)

82 (29.2 %)

74 (32.5 %)

8 (15.1 %)

0.018

 SDH, n (%)

98 (34.9 %)

78 (34.2 %)

20 (37.7 %)

0.476

 SAH, n (%)

137 (48.8 %)

106 (46.5 %)

31 (58.5 %)

0.057

 Contusion, n (%)

125 (44.5 %)

102 (44.7 %)

23 (43.4 %)

0.932

 Intraparenchymal hemorrhage,n(%)

42 (14.9 %)

36 (15.8 %)

6 (11.3 %)

0.477

 Polytrauma, n (%)

144 (51.2 %)

110 (48.2 %)

34 (64.2 %)

0.037

 Abnormal pupil, n (%)

109 (38.8 %)

62 (27.2 %)

47 (88.7 %)

< 0.001

 Hypotension, n (%)

34 (12.1 %)

19 (8.3 %)

15 (28.3 %)

< 0.001

Laboratory investigations

 Lactate, mmol/L

2.1 (0.8-4.0)

1.5 (0.8–3.2)

4.6 (2.9-7.0)

< 0.001

 INR

1.16 (1.07–1.34)

1.14 (1.05–1.26)

1.49 (1.21–1.94)

< 0.001

 APTT, s

29.4 (26.0-35.3)

28.6 (25.4–32.5)

44.4 (29.6–68.3)

< 0.001

 Fibrinogen, mg/dL

134.0

(82.0-182.0)

143.0

(104.8–188.0)

71.0

(50.0-112.0)

< 0.001

 TT, s

18.7 (17.3–21.3)

18.3 (17.1–20.3)

22 (18.8–30.1)

< 0.001

 D-dimer, ug/L

14,040

(3965–22,865)

13,665

(3790–22,348)

16,460

(5280–29,695)

0.127

 PLT, /uL

261.0

(200.0-324.0)

264.5

(208.3-331.3)

210.0

(158.0-298.0)

0.006

 Hgb, g/L

98.0

(81.5–111.0)

101.0

(84.3–113.0)

85.0

(68.0-102.0)

< 0.001

 WBC, *10^9/L

16.6(12.2–21.5)

16.7(12.2–21.1)

15.9(12.7–23.1)

0.486

  1. Data are shown as the median (interquartile range) or a number (percentage)
  2. M month, GCS Glasgow Coma Score, PTS Pediatric Trauma Score, ISS Injury Severity Score, EDH epidural hemorrhage, SDH subdural hemorrhage, SAH subarachnoid hemorrhage, INR International normalized ratio, APTT activated partial thromboplastin time, TT Thrombin time, PLT platelet count, HgB hemoglobin, WBC white blood cell