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Table 3 Univariate and multivariate analyses of factors affecting favourable neurologic outcomes

From: Association between the body mass index and outcomes of patients resuscitated from out-of-hospital cardiac arrest: a prospective multicentre registry study

Variables

Univariate analysis

Multivariate analysis (N = 559)

Unadjusted OR

95% CI for the OR

p-value*

Adjusted OR

95% CI for the OR

p-value*

Age, (per year)

0.946

0.933–0.959

<.001

0.927

0.901–0.953

<.001

Sex, (Female/male)

0.573

0.388–0.844

0.005

1.307

0.617–2.766

0.484

Witnessed arrest (Yes/No)

1.503

1.004–2.249

0.045

0.961

0.461–2.003

0.916

Arrest location (Home/Others)

0.476

0.337–0.672

<.001

0.703

0.366–1.35

0.290

Bystander response (CPR performed/CPR not performed)

2.069

1.463–2.927

<.001

0.658

0.325–1.332

0.245

First monitored rhythm (Shockable/Non-shockable)

14.456

9.456–22.101

<.001

5.869

2.646–13.018

<.001

Hypertension (Present/Absent)

0.573

0.406–0.808

0.002

1.193

0.579–2.459

0.632

Diabetes (Present/Absent)

0.449

0.302–0.667

<.001

0.547

0.252–1.188

0.127

Dyslipidaemia (Present/Absent)

1.685

0.882–3.22

0.114

   

No flow time, (per minute)

0.992

0.97–1.014

0.470

   

Low flow time, (per minute)

0.907

0.891–0.923

<.001

0.962

0.938–0.987

0.003

Pre-hospital ROSC (Observed/Not observed)

19.647

12.791–30.18

<.001

3.762

1.442–9.813

0.007

Pre-hospital adrenaline (Used/Not used)

0.446

0.232–0.858

0.016

1.103

0.319–3.814

0.877

Pre-hospital airway

 Bag-valve mask

Reference

   

 Supraglottic airway

0.769

0.537–1.101

0.152

   

 Endotracheal intubation

0.606

0.337–1.092

0.095

   

Mental state at admission

 Alert

Reference

Reference

 Drowsy to stuporous

0.357

0.136–0.938

0.037

3.924

0.81–19.022

0.006

 Coma

0.036

0.016–0.081

<.001

0.226

0.065–0.782

<.001

Reperfusion attempted

 None

Reference

Reference

 CAG only

9.106

5.818–14.252

<.001

2.636

1.193–5.823

0.057

 CAG and PCI

7.482

4.457–12.561

<.001

5.027

1.869–13.521

0.001

 tPA

0.821

0.305–2.207

0.696

0.353

0.069–1.802

0.021

 TTM (Performed/Not performed)

0.934

0.658–1.327

0.705

   

 pH

632.387

193.43–999.999

<.001

1.706

0.196–14.837

0.628

 Lactate (per mmol/l)

0.858

0.821–0.897

<.001

0.972

0.893–1.058

0.513

 Glucose (per mg/dl)

0.998

0.996–0.999

0.008

0.998

0.994–1.001

0.136

 First systolic BP after ROSC, (per mmHg)

1.007

1.003–1.011

0.003

1.011

0.996–1.025

0.145

 First diastolic BP after ROSC, (per mmHg)

1.024

1.017–1.032

<.001

1.013

0.991–1.036

0.253

 First pulse rate after ROSC, (per beat/min)

1.000

0.994–1.005

0.993

   

BMI, kg/m2

 18.5 to 24.9

Reference

Reference

  < 18.5

0.305

0.155–0.601

0.003

0.656

0.185–2.325

0.358

 25.0 to 29.9

0.929

0.627–1.376

0.366

0.658

0.301–1.441

0.187

  > 30.0

1.401

0.687–2.859

0.040

2.722

0.65–11.401

0.087

  1. Abbreviations: BMI body mass index, CAG coronary angiography, CI confidence interval, CPR cardiopulmonary resuscitation, OR odds ratio, PCI percutaneous coronary intervention, ROSC return of spontaneous circulation, tPA tissue plasminogen activator, TTM targeted temperature management
  2. *p < 0.05 was significant