Table 1 Baseline characteristics stratified by body mass index
Variables | Total (n = 605) | Underweight group (n = 75) | Normal group (n = 333) | Overweight group (n = 163) | Obese group (n = 34) | p-value* |
|---|---|---|---|---|---|---|
Patient domain | ||||||
Age, years, median (IQR) | 63 (53–74) | 71 (62–79) | 63 (54–75) | 61 (51–72) | 56.5 (42–72) | <.001 |
Sex, male (%) | 422 (69.75) | 53 (70.67) | 233 (69.97) | 115 (70.55) | 21 (61.76) | 0.774 |
Witnessed arrest (%) | 449 (74.21) | 55 (73.33) | 244 (73.27) | 125 (76.69) | 25 (73.53) | 0.870 |
Arrest location (n = 601) | ||||||
Home/residence (%) | 320 (53.24) | 48 (64) | 172 (52.12) | 85 (52.47) | 15 (44.12) | 0.185 |
Other (%) | 281 (46.76) | 27 (36) | 158 (47.88) | 77 (47.53) | 19 (55.88) | |
Bystander response (n = 602) | ||||||
CPR by bystander (%) | 307 (51) | 39 (52.7) | 164 (49.4) | 84 (51.53) | 20 (60.61) | 0.645 |
No CPR by bystander (%) | 295 (49) | 35 (47.3) | 168 (50.6) | 79 (48.47) | 13 (39.39) | |
First monitored rhythm (n = 597) | ||||||
Shockable rhythm (%) | 250 (41.88) | 11 (14.86) | 149 (45.29) | 72 (45) | 18 (52.94) | <.001 |
Non-shockable rhythm (%) | 347 (58.12) | 63 (85.14) | 180 (54.71) | 88 (55) | 16 (47.06) | |
Comorbidities (n = 603) | ||||||
Hypertension (%) | 294 (48.76) | 31 (41.33) | 153 (46.08) | 93 (57.41) | 17 (50) | 0.058 |
Diabetes (%) | 190 (31.51) | 16 (21.33) | 102 (30.72) | 60 (37.04) | 12 (35.29) | 0.102 |
Dyslipidaemia (%) | 40 (6.63) | 2 (2.67) | 22 (6.63) | 12 (7.41) | 4 (11.76) | 0.320 |
Pre-ROSC process domain | ||||||
No flow time, minutes, median (IQR) | 7 (5–10) | 6 (3–10) | 7 (5–11) | 7 (5–10) | 6 (5–10) | 0.446 |
Low flow time, minutes, median (IQR) (n = 604) | 25 (12–40) | 26 (18–38) | 24.5 (11–39) | 25 (11–42) | 24.5 (15–54) | 0.655 |
Pre-hospital ROSC (%) | 206 (34.05) | 15 (20) | 129 (38.74) | 51 (31.29) | 11 (32.35) | 0.015 |
Pre-hospital adrenaline use (%) | 62 (10.25) | 5 (6.67) | 39 (11.71) | 16 (9.82) | 2 (5.88) | 0.465 |
Pre-hospital airway | ||||||
Bag-valve mask (%) | 234 (38.68) | 34 (45.33) | 120 (36.04) | 66 (40.49) | 14 (41.18) | 0.427 |
Supraglottic airway (%) | 300 (49.59) | 29 (38.67) | 173 (51.95) | 82 (50.31) | 16 (47.06) | |
Endotracheal intubation (%) | 71 (11.74) | 12 (16) | 40 (12.01) | 15 (9.2) | 4 (11.76) | |
Post-ROSC process domain | ||||||
Mental state at admission | ||||||
Alert (%) | 60 (9.92) | 4 (5.33) | 33 (9.91) | 20 (12.27) | 3 (8.82) | 0.333 |
Drowsy to stuporous (%) | 63 (10.41) | 6 (8) | 30 (9.01) | 22 (13.5) | 5 (14.71) | |
Coma (%) | 482 (79.67) | 65 (86.67) | 270 (81.08) | 121 (74.23) | 26 (76.47) | |
Reperfusion attempted | ||||||
None (%) | 297 (49.09) | 52 (69.33) | 164 (49.25) | 68 (41.72) | 13 (38.24) | 0.002 |
CAG only (%) | 170 (28.1) | 10 (13.33) | 93 (27.93) | 54 (33.13) | 13 (38.24) | |
CAG and PCI (%) | 96 (15.87) | 6 (8) | 60 (18.02) | 26 (15.95) | 4 (11.76) | |
tPA (%) | 42 (6.94) | 7 (9.33) | 16 (4.8) | 15 (9.2) | 4 (11.76) | |
TTM (%) | 225 (37.19) | 17 (22.67) | 122 (36.64) | 72 (44.17) | 14 (41.18) | 0.015 |
pH, median (IQR) (n = 600) | 7.07 (6.92–7.25) | 7.06 (6.95–7.27) | 7.11 (6.91–7.27) | 7.03 (6.9–7.22) | 7.11 (6.98–7.28) | 0.212 |
Lactate, mmol/l, median (IQR) (n = 593) | 10.6 (7.6–14) | 11.7 (9–14.39) | 10.285 (7.2–13.2) | 11 (8.2–15.29) | 9.4 (6.5–13.2) | 0.008 |
Glucose, mg/dl, median (IQR) (n = 603) | 265 (193–338) | 229 (146–313) | 268 (207–335) | 265 (190–378) | 268.5 (228–362) | 0.039 |
First systolic BP after ROSC, mmHg, median (IQR) (n = 590) | 122.5 (92–152) | 130 (80–149) | 120 (90–149) | 124.5 (95.5–160) | 121 (98–156) | 0.482 |
First diastolic BP after ROSC, mmHg, median (IQR) (n = 589) | 75 (59–93) | 79 (56–93) | 74 (56–91) | 77 (60–96) | 72 (57–90) | 0.428 |
First pulse rate after ROSC, beats/min, median (IQR) (n = 586) | 100 (81–123) | 99 (75–132) | 96 (79–120) | 108 (87–124) | 102 (78–116) | 0.062 |