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Table 4 Comparison of number of deaths due to bleeding avoided by tranexamic acid treatment

From: Validation of the BATT score for prehospital risk stratification of traumatic haemorrhagic death: usefulness for tranexamic acid treatment criteria

  Patients treated N (%) N = 104,862 Deaths avoided N (95% CI) Deaths avoided per 10,000 patients N (95% CI) Number needed to treat to avoid one death
Based on predicted probabilities
 Current strategya 9915 (11) 55 (54–57) 5 (5–5) 180
 All prehospital 79,430 (76) 224 (220–228) 21 (21–22) 355
 All in hospital 63,246 (60) 146 (144–149) 14 (14–14) 430
Based on observed probabilities (sensitivity analysis)b
 Current strategya 9915 (11) 168 (157–178) 16 (15–17) 59
 All prehospital 79,430 (76) 323 (305–341) 31 (29–33) 244
 All in hospital 63,246 (60) 240 (226–253) 22 (21–24) 273
  1. NNT Number Needed to Treat
  2. aCurrent strategy observed in the UK-TARN data based on clinical judgment and current guidelines in UK
  3. bSensitivity analysis based on observed deaths due to bleeding