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Table 5 Study variables positively and negatively correlated with SARS-COV-2 positivity

From: Development of machine learning models to predict RT-PCR results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with influenza-like symptoms using only basic clinical data

Positive linear correlation

VARIABLES

Pearson R

VARIABLES

Pearson R

*Fever

0.33

*Sinus Rhythm

0.06

*Body temperature (degree Celsius)

0.27

*Chronic kidney disease

0.05

Lymphocytes percentage

0.26

*Monocytes percentage

0.05

Cough

0.22

Hypertension

0.04

*Total red blood cells count (106/μL)

0.19

Asthma

0.04

*Haemoglobin (g/dL)

0.17

*Age

0.04

Glasgow coma scale (GCS)

0.17

Gastrointestinal symptoms

0.04

*Antibiotics before Emergency Department

0.16

*Calcium channel antagonist

0.04

*Chest pain

0.15

Mean corpuscular haemoglobin concentration (%)

0.03

*Chest X-rays opacity

0.14

Respiratory rate (breaths/min)

0.03

*Sartans

0.13

*Female

0.02

*Systolic blood pressure (mmHg)

0.12

*Headache

0.02

Haematocrit (%)

0.12

*Immunosuppressant drugs

0.02

Arthralgia

0.09

*Hydroxymethylglutaryl-CoA (HMG-CoA)

reductase inhibitors

0.02

*Diastolic blood pressure (mmHg)

0.07

Hematologic malignancy

0.02

P wave present and normal

0.07

*Angiotensin converting enzyme inhibitor

0.01

*5-alpha-reductase inhibitors

0.07

Heart rate (beats per minute)

0.00

Chronic Interstitial lung disease

0.06

  

Negative linear correlation

VARIABLES

Pearson R

VARIABLES

Pearson R

*Total white blood cells count (103/μL)

−0.46

*Dyspnoea

−0.07

*Eosinophils percentages

−0.34

*Ischemic cardiomyopathy

−0.06

Platelets (103/μL)

− 0.33

*Basophils percentage

− 0.06

*Anti-epileptic therapy

−0.25

Diabetes mellitus

−0.06

*Calcium (mg/dL)

−0.22

Creatinine (mg/dL)

−0.06

Mean red blood cell volume (μm3)

−0.21

*Mean corpuscular haemoglobin (pg)

−0.06

Neutrophils percentages

−0.19

*Non Invasive Ventilation

−0.05

*Drugs for psychiatric disorders

−0.19

Autoimmune/inflammatory disease

−0.04

*Chest X-rays pleural effusion

−0.19

Red blood cells distribution width (%)

−0.04

*Chronic obstructive pulmonary disease

−0.17

Anti-arrhythmic drugs

−0.04

*Smoking (active)

−0.15

Syncope

−0.04

*Urea (mg/dL)

−0.14

Glycaemia (mg/dL)

−0.03

*Total bilirubin (mg/dL)

−0.14

*Diuretics

−0.03

Oxygen supplementation

−0.11

Atrial fibrillation

−0.03

*Solid organ tumour

−0.11

C-reactive protein (mg/dL)

−0.03

*Sore throat

−0.10

*Male

−0.02

Human Immunodeficiency Virus

−0.09

Beta blocker

−0.02

Asthenia

−0.08

Anticoagulant therapy

−0.02

Chronic liver disease

−0.08

*Anti-platelets therapy

−0.02

*Sodium (mEq/L)

−0.07

  
  1. Variables were divided according to their positive or negative correlation to the target variable (positivity of RT-PCR for SARS-COV-2) and are listed in decreasing order of positive or negative correlation coefficient, respectively. Asterisks indicate variables included in the TWIST model