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Table 1 Patients’ characteristics for the period before (Period 1, 2005–2007) and after (Period 2, 2012–2014) the implementation of a goal-directed factor-based coagulation algorithm. Values are means with standard deviations or counts and proportions

From: Impact of a goal-directed factor-based coagulation management on thromboembolic events following major trauma

 Period 1 (2005–2007)
n = 344
Period 2 (2012–2014)
n = 428
Age - years42.0 (19.0)51.5 (21.8)
Sex - male268 (78%)315 (74%)
Penetrating trauma29 (8.4%)16 (3.7%)
Injury severity score33 (13)34 (19)
AIS head3 (2)3 (2)
AIS thorax2 (2)2 (2)
AIS abdomen1 (2)1 (1)
AIS extremities1 (1)1 (2)
Laboratory values
 Haemoglobin - g/L111 (29)107 (53)
 Platelet count on entry - 103/mcL211 (68)198 (81)
 Base Excess on entry - mmol/L−4.7 (4.6)−4.4 (5.0)
 Lactate on entry - mmol/L3.2 (2.4)2.6 (2.4)
 Fibrinogen on entry - g/L1.9 (0.8)2.2 (0.9)
 INR on hospital admission1.26 (0.5)1.34 (0.5)
Coagulation factors and allogeneic blood products
 In-hospital TXA3 (0.9%)209 (50%)
 Fibrinogen130 (38%)138 (32%)
 PCC15 (4.4%)39 (9.1%)
 Factor XIII053 (12%)
Transfusion of any allogeneic blood product181 (53%)140 (33%)
 RBC175 (51%)113 (26%)
 PC56 (16%)66 (15%)
 FFP122 (36%)67 (16%)
  1. AIS Abbreviated Injury Scale, RBC Red Blood Cell, PC Platelet Concentrate, FFP Fresh Frozen Plasma, PCC Prothrombin Complex Concentrate, TXA Tranexamic Acid