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Table 2 Included studies examining mixed patient populations or ultrasound for procedural guidance

From: The role of point of care ultrasound in prehospital critical care: a systematic review

First author, year

n

Study type

Aim

US types, providers

Main results

Rating

Mixed populations

 Quick, 2016

149 patients

Controlled (prehospital paramedics vs in-hospital physicians)

To evaluate the ability of ability of in-flight thoracic US to identify pneumothorax (trauma and medical patients)

Lung (PTX), paramedics compared to ED physicians

Gold standard chest CT (n = 116). Prehospital sensitivity of 68% (95% CI 46–85), specificity 96% (95% CI 90–98), accuracy 91% (95% CI 85–95). Physician-based ED US; sensitivity 84% (95% CI 62–94),

specificity 98% (95% CI 93–99), accuracy 96% (95% CI 90–98).

+

 O’Dochertaigh, 2017

455 missions

Cohort

To describe the use of US to support interventions when used by physicians and non-physicians (trauma and medical patients)

Trauma ultrasound and IVC, highly trained physicians and non-physicians (paramedics)

Interventions was supported in US in 26% (95% CI 18–34) of cases when used by non-physicians, and in 45% (95% CI 34–56) when used by physicians (p < 0.006)

0

 Roline, 2013

71 (41 scans)

Cohort

To evaluate the feasibility of bedside thoracic US (trauma and medical patients)

Lung (PTX), prehospital care providers (paramedics?)

In 71 eligible patients, 41 (58%) scans were completed. Level of agreement between flight crew and expert substantial with a kappa of 0.67, (95% CI 0.44–0.90). 54% of images were rated “good”. Causes for not completing US were lack of time or space limitation in aircraft.

+

 Ketelaars, 2013

281 patients, 326 exams

Cohort

To evaluate the impact of US chest examinations on the care of patients in a HEMS service (trauma and cardiac arrest patients)

Heart, lung (PTX), abdomen, experienced physicians

PTX sensitivity 38%, specificity 97%, PPV 90%, NPV 69%.

Treatment plan changed in 60 (21%) patients; in 10 (4%) a chest tube was abandoned; in 10 (4%) the destination for definitive care was changed, in 9 (3%) cardiopulmonary resuscitation was stopped and in 31 (11%) there were other changes.

+

Procedural guidance

 Chenaita, 2012

130 patients

Diagnostic accuracy

To estimate the diagnostic accuracy of US confirmation of gastric tube placement

Abdominal (gastric), experienced physicians

Sensitivity 98.3% (95% CI 94–99.5), specificity 100% (95% CI 75.7–100). PPV 100%, NPV 85.7%. Correlation between gastric tube size and visualization (larger tubes easier to see)

+

 Brun, 2014

32

Controlled study (2-point US vs syringe test)

To estimate the diagnostic accuracy of 2-point US to confirm gastric tube placement

Esophageal, abdominal, physicians

100% visualization of gastric tube in the esophagus, 62.5% in the stomach. X-ray confirmed 28/32 in correct position. US higher diagnostic accuracy than syringe test.

0

 Zadel, 2015

124 patients

Diagnostic accuracy

To assess the sensitivity and specificity of US for confirming endotracheal intubation

Lung (lung sliding and diaphragm excursion), certified physicians

Gold standard, capnography. US sensitivity 100%, specificity 100%, PPV 100%, NPV 100%.

Median US time 30 s.

0

  1. Abbreviations: US ultrasound, PTX pneumothorax, CI confidence interval, ED emergency department, CT computed tomography, IVC inferior vena cava, PPV positive predictive value, NPV negative predictive value
  2. Rating scale: ++ High quality, + Acceptable, − Low quality/unacceptable, 0 Rejected