RIFLE category and component | HES n/N (%) | Saline n/N (%) | Relative risk 95% confidence interval | p | Result |
---|---|---|---|---|---|
RIFLE-R (risk) | 1788/3309 (54.0) | 1912/3335 (57.3) | 0.94 (0.90-0.98) | 0.007 | HES better |
Creatinine increase (x1,5) from baseline | 462/3149 (14.7) | 415/3171 (13.1) | 1.12 (0.99-1.27) | 0.07 | n.s. |
Urine output <0.5 ml/kg/h x 6 h | 1701/3230 (52.7) | 1846/3266 (56.5) | 0.93 (0.89-0.97) | 0.002 | HES better |
RIFLE-I (injury) | 1130/3265 (34.6) | 1253/3300 (38.0) | 0.91 (0.85-0.97) | 0.005 | HES better |
Creatinine increase (x2) from baseline | 245/3149 (7.8) | 191/3171 (6.0) | 1.29 (1.08-1.55) | 0.006 | Saline better |
Urine output <0.5 ml/kg/h x 12 h | 1077/2977 (36.2) | 1200/3024 (39.7) | 0.91 (0.85-0.97) | 0.005 | HES better |