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Table 4 Univariate and multivariate Cox proportional-hazards models for a composite of both periods and within each period (2001-3, 2005-7).

From: Blood product ratio in acute traumatic coagulopathy - effect on mortality in a Scandinavian level 1 trauma centre

  

Univariate

Multivariate

  

HR (95% CI)1

P-value

HR (95% CI)1

P-value

Study period 2001-3 and 2005-7 (n = 220) 7

ISS

score2

1.03 (1.01-1.06)

0.001

1.03 (1.01-1.06)

0.007

Age

years3

1.04 (1.02-1.05)

< 0.001

1.04 (1.03-1.06)

< 0.001

RBC 0-6 h

n4

1.03 (1.01-1.05)

0.013

1.01 (0.96-1.05)

0.756

FFP 0-6 h

n4

1.02 (1.00-1.05)

0.055

0.94 (0.84-1.06)

0.329

PLT 0-6 h

n4

1.06 (1.01-1.11)

0.014

1.12 (0.92-1.36)

0.246

Platelet count

10*109/l5

0.96 (0.93-0.99)

0.007

0.99 (0.96-1.02)

0.353

APTT

> 35 s6

4.60 (2.69-7.88)

< 0.001

3.09 (1.61-5.93)

< 0.001

Study period 2001-3 (n = 79) 7

ISS

score2

1.01 (0.97-1.05)

0.646

1.02 (0.98-1.07)

0.350

Age

years3

1.05 (1.02-1.07)

< 0.001

1.05 (1.03-1.08)

< 0.001

RBC 0-6 h

n4

1.01 (0.95-1.07)

0.817

0.97 (0.88-1.07)

0.520

FFP 0-6 h

n4

0.94 (0.80-1.11)

0.474

0.70 (0.49-0.99)

0.045

PLT 0-6 h

n4

1.20 (0.63-2.26)

0.582

5.30 (0.79-35.32)

0.085

Platelet count

10*109/l5

0.97 (0.92-1.03)

0.371

0.97 (0.91-1.02)

0.247

APTT

> 35 s6

3.42 (1.28-9.15)

0.014

2.47 (0.66-9.21)

0.177

Study period 2005-7 (n = 141) 7

ISS

score2

1.04 (1.02-1.07)

0.001

1.04 (1.01-1.07)

0.020

Age

years3

1.03 (1.01-1.05)

< 0.001

1.04 (1.02-1.06)

< 0.001

RBC 0-6 h

n4

1.03 (1.01-1.05)

0.016

1.04 (0.97-1.12)

0.223

FFP 0-6 h

n4

1.02 (1.00-1.05)

0.085

0.98 (0.87-1.11)

0.749

PLT 0-6 h

n4

1.05 (1.00-1.10)

0.061

0.95 (0.76-1.19)

0.676

Platelet count

10*109/l5

0.95 (0.92-0.99)

0.011

0.98 (0.95-1.02)

0.320

APTT

> 35 s6

5.04 (2.62-9.68)

< 0.001

3.41 (1.55-7.51)

0.002

  1. 1Relative hazards with 95% confidence intervals (HR (95% CI)) and p-values are shown for all variables, with p-values in bold for variables with p < 0.05. 2One unit increase in ISS, 3One years older, 4One more unit of the respective blood component, 5A 10*109/l increase in platelet count, 6APTT > 0.35 s (above reference range). 7Each univariate and multivariate Cox models only included patients with complete data (i.e., the same patients were included in each univariate and multivariate analyses)